Many
of the pesticides are toxic to organisms other than those especially targeted.
One of the greatest concerns with the development and use of these substances
is their slow breakdown and their ability to accumulate in organisms.
A major problem of pesticide
use is that their widespread use accelerates the development of genetic
resistance to pesticides. Because
of genetic resistance, many insecticides (such as DDT) no longer protect people
from insect-transmitted diseases (malaria, for example) in some parts of the
world.
Another
problem is that broad-spectrum
insecticides kill natural predators and parasites that help control the
populations of pest species.
Also,
pesticides do not stay put. According
to USDA, no more than 2% of the insecticide applied to crops by aerial or
ground spraying reaches the target pests. Also, less than 5% of herbicides
applied to crops reach the target weeds.
Pesticides that miss their target pests
can end up in the air, surface water, groundwater, bottom sediments, food, and
nontarget organisms, including humans and wildlife: at
high enough levels, most pesticides can be toxic to humans, cause nervous
system disorders (especially behavioral disorders), affects immune system, can
cause cancer in animals, have adverse reproductive and developmental effects in
wildlife, signs of growth irregularity, loss in biomass, or death to plants, in
an extreme case of contamination, the number and activity of soil
microorganisms may be reduced to essentially zero.
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